Tschaharganeh, Darjus F.: search on Z-Library

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1

Inducible in vivo genome editing with CRISPR-Cas9

Dow, Lukas E, Fisher, Jonathan, O'Rourke, Kevin P, Muley, Ashlesha, Kastenhuber, Edward R, Livshits, Geulah, Tschaharganeh, Darjus F, Socci, Nicholas D, Lowe, Scott W

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 1.85 MB

english, 2015

2

Prediction of potent shRNAs with a sequential classification algorithm

Pelossof, Raphael, Fairchild, Lauren, Huang, Chun-Hao, Widmer, Christian, Sreedharan, Vipin T, Sinha, Nishi, Lai, Dan-Yu, Guan, Yuanzhe, Premsrirut, Prem K, Tschaharganeh, Darjus F, Hoffmann, Thomas,

Journal:

Nature Biotechnology

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

3

Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling

Weissmueller, Susann, Manchado, Eusebio, Saborowski, Michael, Morris, John P., Wagenblast, Elvin, Davis, Carrie A., Moon, Sung-Hwan, Pfister, Neil T., Tschaharganeh, Darjus F., Kitzing, Thomas, Aust,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.46 MB

english, 2014

4

p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer

Tschaharganeh, Darjus F., Xue, Wen, Calvisi, Diego F., Evert, Matthias, Michurina, Tatyana V., Dow, Lukas E., Banito, Ana, Katz, Sarah F., Kastenhuber, Edward R., Weissmueller, Susann, Huang, Chun-Hao

Journal:

Year:

2014

Language:

english

File:

PDF, 5.43 MB

english, 2014

5

Lack of interleukin-6/glycoprotein 130/signal transducers and activators of transcription-3 signaling in hepatocytes predisposes to liver steatosis and injury in mice

Daniela C. Kroy, Naiara Beraza, Darjus F. Tschaharganeh, Leif E. Sander, Stephanie Erschfeld, Arne Giebeler, Christian Liedtke, Hermann E. Wasmuth, Christian Trautwein, Konrad L. Streetz

Journal:

Year:

2010

Language:

english

File:

PDF, 2.90 MB

english, 2010

6

Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer

Dow, Lukas E., O’Rourke, Kevin P., Simon, Janelle, Tschaharganeh, Darjus F., van Es, Johan H., Clevers, Hans, Lowe, Scott W.

Journal:

Year:

2015

Language:

english

File:

PDF, 5.83 MB

english, 2015

7

p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer

Tschaharganeh, Darjus F., Xue, Wen, Calvisi, Diego F., Evert, Matthias, Michurina, Tatyana V., Dow, Lukas E., Banito, Ana, Katz, Sarah F., Kastenhuber, Edward R., Weissmueller, Susann, Huang, Chun-Hao

Journal:

Year:

2016

Language:

english

File:

PDF, 1.49 MB

english, 2016

8

p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression

Moon, Sung-Hwan, Huang, Chun-Hao, Houlihan, Shauna L., Regunath, Kausik, Freed-Pastor, William A., Morris, John P., Tschaharganeh, Darjus F., Kastenhuber, Edward R., Barsotti, Anthony M., Culp-Hill, R

Journal:

Year:

2018

Language:

english

File:

PDF, 5.84 MB

english, 2018

9

Non-Cell-Autonomous Tumor Suppression by p53

Lujambio, Amaia, Akkari, Leila, Simon, Janelle, Grace, Danielle, Tschaharganeh, Darjus F., Bolden, Jessica E., Zhao, Zhen, Thapar, Vishal, Joyce, Johanna A., Krizhanovsky, Valery, Lowe, Scott W.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.94 MB

english, 2013

10

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

Huang, Chun-Hao, Lujambio, Amaia, Zuber, Johannes, Tschaharganeh, Darjus F., Doran, Michael G., Evans, Michael J., Kitzing, Thomas, Zhu, Nan, de Stanchina, Elisa, Sawyers, Charles L., Armstrong, Scott

Journal:

Genes & Development

Year:

2014

Language:

english

File:

PDF, 2.03 MB

english, 2014

11

Chelator-Free Radiolabeling of SERRS Nanoparticles for Whole-Body PET and Intraoperative Raman Imaging

Wall, Matthew A., Shaffer, Travis M., Harmsen, Stefan, Tschaharganeh, Darjus-Felix, Huang, Chun-Hao, Lowe, Scott W., Drain, Charles Michael, Kircher, Moritz F.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

12

Quantitative self-assembly prediction yields targeted nanomedicines

Shamay, Yosi, Shah, Janki, Işık, Mehtap, Mizrachi, Aviram, Leibold, Josef, Tschaharganeh, Darjus F., Roxbury, Daniel, Budhathoki-Uprety, Januka, Nawaly, Karla, Sugarman, James L., Baut, Emily, Neiman,

Journal:

Nature Materials

Year:

2018

Language:

english

File:

PDF, 2.85 MB

english, 2018

13

Glucose catabolism in liver tumors induced by c-MYC can be sustained by various PKM1/PKM2 ratios and pyruvate kinase activities

Méndez-Lucas, Andrés, Li, Xiaolei, Hu, Junjie, Che, Li, Song, Xinhua, Jia, Jiaoyuan, Wang, Jingxiao, Xie, Chencheng, Driscoll, Paul C., Tschaharganeh, Darjus F, Calvisi, Diego F, Yuneva, Mariia, Chen,

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 5.93 MB

english, 2017

14

DNAJB1–PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma

Kastenhuber, Edward R., Lalazar, Gadi, Houlihan, Shauna L., Tschaharganeh, Darjus F., Baslan, Timour, Chen, Chi-Chao, Requena, David, Tian, Sha, Bosbach, Benedikt, Wilkinson, John E., Simon, Sanford M

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.97 MB

english, 2017

15

Nuclear expression of the ubiquitin ligase seven in absentia homolog (SIAH)-1 induces proliferation and migration of liver cancer cells

Antje Brauckhoff, Mona Malz, Darjus Tschaharganeh, Nisar Malek, Achim Weber, Marc-Oliver Riener, Christopher Soll, Jana Samarin, Michaela Bissinger, Jan Schmidt, Thomas Longerich, Volker Ehemann, Pete

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

16

Multiplexed orthogonal genome editing and transcriptional activation by Cas12a

Breinig, Marco, Schweitzer, Anabel Y., Herianto, Anna M., Revia, Steffie, Schaefer, Lisa, Wendler, Lena, Cobos Galvez, Ana, Tschaharganeh, Darjus F.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.13 MB

english, 2018

17

Non-specific effects of siRNAs on tumor cells with implications on therapeutic applicability using RNA interference

Darjus Tschaharganeh, Volker Ehemann, Tanja Nussbaum, Peter Schirmacher, Kai Breuhahn

Journal:

Pathology & Oncology Research

Year:

2007

Language:

english

File:

PDF, 146 KB

english, 2007

18

Coordinated Tumor Suppression by Chromosome 8p

Tschaharganeh, Darjus F., Bosbach, Benedikt, Lowe, Scott W.

Journal:

Year:

2016

Language:

english

File:

PDF, 358 KB

english, 2016

19

MHC class II expression in pancreatic tumors: a link to intratumoral inflammation

Matthias M. Gaida, Thilo Welsch, Esther Herpel, Darjus F. Tschaharganeh, Lars Fischer, Peter Schirmacher, G. Maria Hänsch, Frank Bergmann

Journal:

Virchows Archiv

Year:

2012

Language:

english

File:

PDF, 799 KB

english, 2012

20

Expression of Galectin-3 in Pancreatic Ductal Adenocarcinoma

Matthias M. Gaida, Sylvia T. Bach, Frank Günther, Billur Baseras, Darjus F. Tschaharganeh, Thilo Welsch, Klaus Felix, Frank Bergmann, Gertrud M. Hänsch, Moritz N. Wente

Journal:

Pathology & Oncology Research

Year:

2012

Language:

english

File:

PDF, 432 KB

english, 2012

21

Using CRISPR/Cas to study gene function and model disease in vivo

Tschaharganeh, Darjus F., Lowe, Scott W., Garippa, Ralph J., Livshits, Geulah

Journal:

Year:

2016

Language:

english

File:

PDF, 659 KB

english, 2016

22

TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation

Faletti, Laura, Peintner, Lukas, Neumann, Simon, Sandler, Sandra, Grabinger, Thomas, Mac Nelly, Sabine, Merfort, Irmgard, Huang, Chun-Hao, Tschaharganeh, Darjus, Kang, Tae-Won, Heinzmann, Florian, D’A

Journal:

Cell Death and Disease

Year:

2018

Language:

english

File:

PDF, 1.69 MB

english, 2018

23

A Pipeline for Drug Target Identification and Validation

Manchado, Eusebio, Huang, Chun-Hao, Tasdemir, Nilgun, Tschaharganeh, Darjus F., Wilkinson, John E., Lowe, Scott W.

Journal:

Cold Spring Harbor Symposia on Quantitative Biology

Year:

2017

Language:

english

File:

PDF, 417 KB

english, 2017

24

Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures

Billon, Pierre, Nambiar, Tarun S., Hayward, Samuel B., Zafra, Maria P., Schatoff, Emma M., Oshima, Koichi, Dunbar, Andrew, Breinig, Marco, Park, Young C., Ryu, Han S., Tschaharganeh, Darjus F., Levine

Journal:

Year:

2020

File:

PDF, 3.48 MB

2020

25

Polymorphonuclear neutrophils promote dyshesion of tumor cells and elastase-mediated degradation of E-cadherin in pancreatic tumors

Gaida, Matthias M., Steffen, Thomas Große, Günther, Frank, Tschaharganeh, Darjus F., Felix, Klaus, Bergmann, Frank, Schirmacher, Peter, Hänsch, Gertrud M.

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

26

Aberrant Cell Cycle Progression and Endoreplication in Regenerating Livers of Mice That Lack a Single E-Type Cyclin

Yulia A. Nevzorova, Darjus Tschaharganeh, Nikolaus Gassler, Yan Geng, Ralf Weiskirchen, Piotr Sicinski, Christian Trautwein, Christian Liedtke

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 4.38 MB

english, 2009

27

Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma

Tschaharganeh, Darjus Felix, Chen, Xin, Latzko, Philipp, Malz, Mona, Gaida, Matthias Martin, Felix, Klaus, Ladu, Sara, Singer, Stephan, Pinna, Federico, Gretz, Norbert, Sticht, Carsten, Tomasi, Maria

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 1.52 MB

english, 2013

28

Imaging of Liver Tumors Using Surface-Enhanced Raman Scattering Nanoparticles

Andreou, Chrysafis, Neuschmelting, Volker, Tschaharganeh, Darjus-Felix, Huang, Chun-Hao, Oseledchyk, Anton, Iacono, Pasquale, Karabeber, Hazem, Colen, Rivka R, Mannelli, Lorenzo, Lowe, Scott W., Kirch

Journal:

Year:

2016

Language:

english

File:

PDF, 2.48 MB

english, 2016

29

Glycoprotein 130–dependent pathways in host hepatocytes are important for liver repopulation in mice

Darjus F. Tschaharganeh, Michaela Kaldenbach, Stephanie Erschfeld, Jens J. W. Tischendorf, Christian Trautwein, Konrad L. Streetz

Journal:

Liver Transplantation

Year:

2010

Language:

english

File:

PDF, 963 KB

english, 2010

30

The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma

Banito, Ana, Li, Xiang, Laporte, Aimée N., Roe, Jae-Seok, Sanchez-Vega, Francisco, Huang, Chun-Hao, Dancsok, Amanda R., Hatzi, Katerina, Chen, Chi-Chao, Tschaharganeh, Darjus F., Chandwani, Rohit, Tas

Journal:

Year:

2018

Language:

english

File:

PDF, 6.33 MB

english, 2018

31

Lack of Glycoprotein 130/Signal Transducer and Activator of Transcription 3-Mediated Signaling in Hepatocytes Enhances Chronic Liver Injury and Fibrosis Progression in a Model of Sclerosing Cholangitis

Werner Plum, Darjus F. Tschaharganeh, Daniela C. Kroy, Eva Corsten, Stephanie Erschfeld, Uta Dierssen, Hermann Wasmuth, Christian Trautwein, Konrad L. Streetz

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

32

The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma

Banito, Ana, Li, Xiang, Laporte, Aimée N., Roe, Jae-Seok, Sanchez-Vega, Francisco, Huang, Chun-Hao, Dancsok, Amanda R., Hatzi, Katerina, Chen, Chi-Chao, Tschaharganeh, Darjus F., Chandwani, Rohit, Tas

Journal:

Year:

2018

Language:

english

File:

PDF, 1.89 MB

english, 2018

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